Filter integrity test method
Filter integrity testing methods are classified in two types, 1) Destructive test 2) Non destructive test The goal of filter integrity test is to ensure product quality, product performance and reduce the risk. Filter or filtration membrane are made up of PTFE (polytetrafluoroethylene) or PVDF (polyvinylidene fluoride), PTFE is more hydrophobic than PVDF. Destructive test is generally performed by manufacturer based on statistical sample from each lot of membrane and fabricated devices produced. Non destructive testing perform by manufacturer on each sterilizing grade filter prior to sale to ensure it's integrity. (Ref. Merk Millipore. Com "Integrity Testing methods".) The product deliver to end user are integrity tested but once the product exit from manufacturing company there will be a chance of damage during shipment/supply to end user so it's preferred to perform pre and post use integrity by the end user to ensure product integrity. 1) Destructive filter integ